The timeline would suggest the addition of the resource dungeon isle, which wasn't immediately present upon the release of the Dungoneering skill/Daemonheim, would not have had any impact on the placement of the 'heim' and seek clue.
I can't imagine the 'heim' and seek clue was touched by the Sept 2020 rework, and would go as far to say that it would seem likely that it has not been touched since its inception.
I tried looking through old maps from https://runescape.wiki/w/World_map/History to see if there was something lying somewhere around that may be of interest, but I didn't find anything of use.
2) Rows around Slayer Tower before release of Daemonheim/tower graphical rework
I wondered whether a player before the release of Daemonheim was able to walk up further than the 13 degrees, 11 mins north row (either northwest or northeast of the Slayer Tower, but particularly towards the NE) and whether that would have affected the placement of the clue.
On Old School, I went up northwest of the Slayer Tower (in the wildy):
13 degrees, 28 minutes north (furthest north I can go)
29 degrees, 43 minutes east (furthest east I can go)
These borders have not changed. The same rows are still accessible in today's game. One cannot go east of 29 degrees, 43 mins east still. Now I tested northeast of the Slayer Tower:
13 degrees, 11 minutes north (furthest north I can go)
31 degrees, 45 minutes east (furthest west I can go)
It is still not possible to roam further north than 13 degrees, 11 mins north there, so that part has been unchanged. It is no longer possible to go to 31 degrees, 45 minutes east in that area, unless you roam a bit further south, but it seems unlikely that would have had an impact on the clue placement. The furthest west you can go now there is 31 degrees, 46 mins east.
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22-May-2021 22:52:36