Well it would be extremely difficult to recolonise the Wilderness. Since it's basically the RS equivalent of a nuclear fallout site. Although there is evidence of the Wilderness "healing" it is still far from liveable land nor is it attractive to settlers. The only ones that have been willing to settle in the Wilderness are outcasts or people who don't like to be disturbed like bandits, pirates, smugglers and dark knights.
Not to mention even if someone tried to settle the Wilderness they'd be vulnerable to all the monsters plus all the factions I mentioned above. Plus there are also the many dangerous dungeon still around.
So a full scale settlement can't happen. However a colony could make for a fun minigame/quest. However that brings us to the first point.
The statement below is false.
The statement above is true.
13-Jul-2017 11:36:26