Essentially this is the guide that I used but, I modified it of course to create a bit more freedom during the kills
https://www.youtube.com/watch?v=lD3F5ZPaI6g#t=271
The difference between my set-up and his is a lot of things but the strategy is the same.
http://puu.sh/fsiTh.jpg
I use tetsu given it is cheap and provides an excellent protection bonus. You can switch this to malvolent but, this boss in my eyes is not worth using that item since you can barely create a profitable return as is anyways. I suggest tetsu but can use malv if you so wish. The kill speed difference for me here is around 1-2 seconds (using malv compared to tetsu).
The scrimshaw is "Vamp".
Upon killing the boss - I advise you to turn "auto retaliate- off". Evidently, the boss takes long enough to attack between her magic attacks that you will begin to try to attack the minions. This can become increasingly annoying if you are using the ability "destroy" or "assault" - as it will stop you middle of use. Turn back on auto retaliate when boss is kill then kill minions. Turn off turmoil upon killing the minions as prayer is scarce. Effectively utilize "ring of vigour" upon zerking.
--WILL ADD MORE ONCE I FINISH THIS INSTANCE--
Support Please :3 Or at least read it... RL Idea:3316