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Alcohol is a leading cause of suicide(nearly 2/10 alcoholics will commit suicide) and permanent/irreversible states of delusion and eating disorders and multiple forms of cancer and cardiovascular disorders and fetal death/defects and insomnia and erectile dysfunction and domestic violence and car crashes among other problems. Ethanol also produces a carcinogenic and toxic byproduct which can permanently alter genes in a harmful way and has been shown to increase instances of Alzheimer's disease and schizophrenia in some people with genetic risks.