Quite a few events happen earlier or not at all in FMA Brotherhood, at least until Greed (which also happens earlier) after which the series changes quite a lot and goes down a different path compared to the first anime.
The antagonist is different, and a few characters have different designs and motives. Several key things from the first series are also different.
I'll just say that the series might seem too fast and rushed at first, but that's a side-effect of the overlapping content between the 2 series; the producers didn't want to churn out more of the same, so they whizzed through the overlap.
27-Oct-2010 08:34:45